cmtk-glm(1)


NAME

   glm - General Linear Model

SYNOPSIS

   glm [options] ctlfile imgfile_pattern [ctlfile imgfile_pattern ...]

DESCRIPTION

   Statistical  modeling  of  pixel intensities in multiple images using a
   General Linear Model.

   The independent variables of the model  are  defined  in  one  of  more
   control  files.  Each  control file is a text file with one whitespace-
   separated column per independent variable.

   The first line of the control file defines the  variable  names,  i.e.,
   the  labels  that  identify each variable. Each following line contains
   one value per independent variable.

   Example:

     ID  age  sex
     01  20   0
     02  30   1

   Each control file name is followed by a  file  name  pattern.  In  that
   pattern,  a  single '%s' place holder is replaced by the value found in
   the first column of each control file row. The resulting string is  the
   path  of  the image read and associated with the model variables listed
   on that particular control file line.

   Using    the    above    control    file    example,    the     pattern
   'images/subject%s.nii'   would    expand   to   the  image  file  names
   'images/subject01.nii' and 'images/subject02.nii'.

   Multiple control files can be used, each with a  different  image  file
   pattern.

OPTIONS

   Global Toolkit Options (these are shared by all CMTK tools)
   --help
        Write list of basic command line options to standard output.

   --help-all
        Write  complete list of basic and advanced command line options to
        standard output.

   --wiki
        Write list of command line options to standard output in MediaWiki
        markup.

   --man
        Write man page source in 'nroff' markup to standard output.

   --version
        Write toolkit version to standard output.

   --echo
        Write the current command line to standard output.

   --verbose-level <integer>
        Set verbosity level.

   --verbose, -v
        Increment verbosity level by 1 (deprecated; supported for backward
        compatibility).

   --threads <integer>
        Set maximum number of parallel  threads  (for  POSIX  threads  and
        OpenMP).

   Input Settings
   --crop <string>, -c <string>
        To save space/time, crop images: x0,y0,z0,x1,y1,z2

   Model Settings
   --normalize, -n
        Normalize model parameters w.r.t. data variances.

   --exp, -e
        Use exponential model rather than linear model.

   Selection of Independent Variables
   --exclude-constant, -x
        Exclude automatic constant parameter from model.

   --ignore-parameter <string>, -i <string>
        Ignore parameter with given NUMBER (0..n-1). Can be repeated.

   --select-parameter <string>, -s <string>
        Select parameter with given NAME for model. Can be repeated.

   Output Settings
   --output-pattern <string>, -O <string>
        Filename pattern for output.

          %s is replaced with image type ('fstat', 'tstat', or 'param')
          %d  is  replaced  with independent variable number (0 for entire
        model)
          %s is replaced  with  independent  variable  name  ('model'  for
        entire model)

        [Default: model_%s_%02d_%s.nii ]

AUTHORS

   Torsten  Rohlfing,  with  contributions  from  Michael  P.  Hasak, Greg
   Jefferis, Calvin R. Maurer, Daniel B. Russakoff, and Yaroslav Halchenko

LICENSE

   http://www.fsf.org/licensing/licenses/gpl.html

BUGS

   Report bugs at http://nitrc.org/projects/cmtk/

ACKNOWLEDGMENTS

   CMTK is developed with support from the  NIAAA  under  Grant  AA021697,
   National  Consortium on Alcohol and Neurodevelopment in Adolescence (N-
   CANDA): Data Integration Component. From April 2009  through  September
   2011, CMTK development and maintenance was supported by the NIBIB under
   Grant EB008381.





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